A significant component of the research effort of the National Institute of Allergy and Infectious Diseases (NIAID) is devoted to the pathogenesis of HIV (human immunodeficiency virus) disease. Studies on pathogenesis address the complex mechanisms that result in the destruction of the immune system of an HIV-infected person. A detailed understanding of HIV and how it establishes infection and causes AIDS (acquired immunodeficiency syndrome) is crucial to identifying and developing effective drugs and vaccines to fight HIV and AIDS. This fact sheet summarizes the state of knowledge in this area.
(Scientific terms printed in bold-faced type are defined in the Glossary at the end of this document.)
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